As long as I'm on a kick with games that make me think of movies, I've got to mention Micronytes. This is an absolutely incredible platformer that just reeks of Fantastic Voyage.
Instead of a blood clot in the brain, there are these (assumedly evil) green, anthropomorphized green blobs munching on all the tasty red stuff inside of an unnamed victim. How to defeat them? Send in some rotund, faceless gents in all white suits to eradicate the problem.
Join me after the break to see just how detailed this adventure becomes.